Table of Contents

HK J Paediatr (New Series)
Vol 18. No. 4, 2013

HK J Paediatr (New Series) 2013;18:210-216

Original Article

Level of Non-high-density-lipoprotein Cholesterol and Its Related Factors in Chinese Han Students

YL Fang, L Liang, JF Fu, CX Gong, F Xiong, GL Liu, FH Luo, SK Chen


Objective: The aim of this study was to investigate the concentration of non-high-density lipoprotein cholesterol in Chinese Han students of varying ages and genders, and to find out its related factors. Methods: We examined 20208 Han students (10573 boys and 9635 girls) aged between 6-17 years old who came from 6 districts throughout China. The examination, performed during 2009-2010, involved a clinical examination and self-administered questionnaire. Based on the criteria defined by the American Academy of Pediatrics for children and adolescents in 2011, we defined high non-high-density lipoprotein cholesterol (total cholesterol minus high-density lipoprotein cholesterol) at a level ≥3.75 mmol/l. We set gender, age, obesity, physical activities, sleep duration, eating patterns and sedentary activities as related factors and performed logistic regression analysis. Result: The percentage of high non-high-density lipoprotein cholesterol was 4.1% in 6-17 years old children and adolescents in China. Non-high-density lipoprotein cholesterol concentration was significantly higher in girls than boys. Biological maturity was positively associated with non-high-density lipoprotein cholesterol concentration. Gender, weekly sport frequency, eating patterns, biological maturity and obesity were the related factors of high non-high-density lipoprotein cholesterol concentrations. Conclusion: The concentrations of non-high-density lipoprotein cholesterol in children and adolescents are strongly determined by gender. Obesity, gender and biological maturity contributed to the variance in non-high-density lipoprotein cholesterol and should be considered in future evaluation of non-high-density lipoprotein cholesterol status. Children and adolescents who did more sports and ate more vegetables were less likely to have a higher non-high-density lipoprotein cholesterol level.

目的:這項研究旨在調查不同年齡和性別的中國漢族學生,其非高密度脂蛋白膽固醇的濃度,並尋找相關因素。方法:我們檢查了來自中國6個地區的20208名漢族學生(10573名男孩和9635名女孩),年齡介乎6-17歲。2009- 2010年期間進行檢查,包括臨床檢查和自填問卷。依照2011年美國兒科學會定義的標準,我們定義高非高密度脂蛋白膽固醇水平(總膽固醇減去高密度脂蛋白膽固醇)?.75mmol/L。相關因素如性別、年齡、肥胖、體力活動、睡眠時間、飲食模式和久坐的活動,都被納入進行回歸分析。結果:中國6-17歲的兒童和青少年高非高密度脂蛋白膽固醇的百分比為4.1%。非高密度脂蛋白膽固醇濃度,男生顯著高於女生。生理成熟度與非高密度脂蛋白膽固醇濃度呈正相關。性別、每週的運動頻率、飲食模式、生理成熟和肥胖是高非高密度脂蛋白膽固醇濃度的相關因素。結論:性別是影響兒童和青少年的非高密度脂蛋白膽固醇濃度的最主要因素。肥胖、性別和生理成熟度對非高密度脂蛋白膽固醇也有一定影響,今後評估非高密度脂蛋白膽固醇的狀態時應考慮上述因素。多做運動,多吃蔬菜的兒童和青少年出現高非高密度脂蛋白膽固醇水平的機會較低。

Keyword : Children; Lifestyle; Non-high-density-lipoprotein cholesterol; Obesity



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