Table of Contents

HK J Paediatr (New Series)
Vol 17. No. 2, 2012

HK J Paediatr (New Series) 2012;17:103-108

Original Article

Surgery for Wilms Tumour in Children in a Tertiary Centre in Hong Kong: A 15-year Retrospective Review

KW Chan, KH Lee, JW Mou, YH Tam


Objective: To study the surgical aspect in the management of Wilms tumour in children. Methods: A retrospective study was conducted for all children who underwent nephrectomy for Wilms tumours in a university teaching hospital in Hong Kong from January 1996 to June 2011. Results: A total of 13 children (6 boys and 7 girls) were studied. The median age at diagnosis was 37 months (range, 9 months-10 years). Two children had stage I disease, 4 had stage II disease, 4 had stage III disease, 1 had stage IV and 2 had stage V disease. Pre-operative chemotherapy was given to children with stage III or above disease. The median tumour size was 10 cm (range, 5 to 17 cm). Unilateral radical nephrectomy was performed in children with unilateral disease. Children with bilateral disease underwent nephron-sparing surgery. Lymph node biopsies were performed in 8 cases while 1 had positive lymph node involvement. There was no intraoperative tumour rupture. Intraoperative complications including small bowel injury (n=1), diaphragmatic injury (n=1) and major bleeding that required transfusion (n=2). Post-operatively, all children received chemotherapy. Children with advance disease also received radiotherapy. There was no post-operative surgical complication. At a median follow-up of 76 months, all children survived and 2 children had distant tumour recurrence. Conclusion: This study provides updated surgical experience in the management of Wilms tumour. Zero intraoperative tumour ruptured rate was achieved. With multidisciplinary management, the long term outcome of Wilms tumour was excellent.

Keyword : Children; Surgery; Tumour; Wilms

Abstract in Chinese


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