LY Siu, LW Siu, NS Kwong

Abstract

Objective: To evaluate the reliability of Minolta JM-103 Jaundice Meter as a screening tool for healthy near term (>=35 weeks) to term neonates who presented to the Maternal and Child Health Centres (MCHCs) because of jaundice on day 3-14. Methods: This retrospective observational study studied the correlation between the total serum bilirubin (TSB) measurements and the paired transcutaneous bilirubin (TcB) measurements obtained in the MCHCs between January 2008 and July 2009. Findings: Transcutaneous bilirubin showed a low correlation with TSB (r=0.392) in 253 neonates aged between 3 to 7 days old. The corresponding correlation was moderate (r=0.674) in 95 neonates aged between 8 to 14 days old. The mean difference between TcB obtained in the MCHCs and TSB was 15.6 μmol/L and 18.6 μmol/L in the first and second weeks, respectively; indicating a uniform tendency for JM-103 to overestimate TSB. The corresponding limits of agreement were between -42.9 and 73.1 μmol/L in the former group and -42.1 and 79.4 μmol/L in the latter group. Conclusion: JM-103 cannot be considered a substitute for laboratory measurement of TSB, but appears to be useful as a screening tool in the studied population.

目的：評估美能達JM-103黃疸測定儀作為篩查工具，對於出生後3-14天，因黃疸於母嬰健康院（MCHCs）求診的接近足月（>=35孕周）和足月嬰兒的新生兒黃疸評估的可靠性。方法：此回顧性研究的目的是瞭解2008 年1月至2009年7月間，母嬰健康院的血清總膽紅素（TSB）與配對經皮測定膽紅素（TcB）數值之間的聯繫。結果：在253名日齡3-7天的新生兒裡，經皮測定膽紅素與TSB的相關係數（r=0.392）較低。而在95名日齡8-14天的新生兒裡，其相關係數則為0.674。在MCHCs記錄的TcB和TSB 於第1周和第2周的雙差均值分別為15.6 μmol/L 和18.6 μmol/L ，顯示JM-103的測定值易高於TSB。在第1組和第2組的相應一致性限值分別為-42.9-73.1 μmol/L和-42.1-79.4 μmol/L。結論： JM-103不能替代實驗室TSB的測量，但是在病人中進行研究，則可以是一項有用的篩查工具。