LY Siu, LW Siu, sk Au, kw Li, TK Tsui, YY Chang, gp Lee, NS Kwong

Abstract

Objective: To evaluate the reliability of Minolta JM-103 Jaundice Meter as a screening tool for neonatal jaundice in preterm Chinese neonates on day 0-14. Methods: This prospective study studied the correlation between the total serum bilirubin (TSB) measurements and the paired transcutaneous bilirubin measurements obtained at the forehead (TcB_F) and sternum (TcB_S) between April and September 2009. Findings: 110 pairs of TcB_F, TcB_S and TSB measurements were evaluated in 30 preterm newborns. Both TcB measurements were significantly correlated with TSB, with a correlation coefficient of 0.81 and 0.83 for TcB measurements obtained at the forehead and sternum, respectively. The mean of the difference of the pairs (TcB_F minus TSB) and (TcB_S minus TSB) were 9.30 and 20.18 μmol/L, respectively. The corresponding standard deviation measured 27.10 and 27.46 at p<0.01, respectively; the JM-103 tended to overestimate TSB. Conclusion: TcB correlates significantly with TSB in preterm neonates and JM-103 appears to be useful as a screening tool in preterm (<35 weeks) neonates.

目的: 評估美能達JM-103黃疸測定儀作為測定工具，對於中國0-14天早產兒的新生兒黃疸評估的可靠性。方法：此前瞻性研究的目的是瞭解2009年4-9月間，早產兒血清總膽紅素（TSB ）與在前額（TcB_F）和胸骨（TcB_S）經皮測定膽紅素數值之間的聯繫。結果：在30個早產的新生兒中，110對TcB_F, TcB_S 和 TSB的測定值作了相應的評估。2種TcB的測定值明顯跟TSB相關，前額和胸骨的TcB測定值的與TSB相關係數分別為0.81和 0.83。雙差均值（TcB_F 減去 TSB）和（TcB_S 減去 TSB）分別為9.30 和 20.18 μmol/L。相應的標準差分別為27.10 和 27.46 ，p<0.01。JM-103的測定值易高於TSB。結論: 在早產兒，TcB 與TSB的測定具有明顯的相關性，JM-103 似乎是有效的早產兒（<35 weeks）膽紅素的測定工具。