B Falakaflaki, A Ahmadiafshar

Abstract

Objective: Human milk provides protection against infections. Protection against gastrointestinal and respiratory infections and otitis media is well documented. Protection against urinary tract infection is less recognised. The aim of this study was to assess the possible protective effect of breast feeding against urinary tract infection in children. Methods: In this prospective case-control study, cases were 50 infants with documented urinary tract infection during the first year of life and controls consisted of 50 healthy children less than 1 year. The children according to the type of feeding were categorised into three groups: breast feeding, formula feeding, mixed feeding. Results: Breast fed infants had significantly a lower risk of urinary tract infection (UTI) than formula fed and mix feeding infants (OR=0.1 95%CI, 0.027-0.329 and OR=0.33 95%CI, 0.124-0.866 respectively). Mix-fed infants had a decreased risk of UTI than formula-fed infants (OR=0.3 95%CI, 0.091-0.92).A longer duration of breast feeding gave a lower risk of UTI (OR=0.29 95%CI, 0.121-0.714). Conclusion: On the basis of this data, breast feeding has a protective effect against urinary tract infection.

目的：母乳對感染有保護作用。母乳對胃腸道、呼吸道感染和中耳炎的保護作用已有很多報導。其對泌尿道的保護作用較少認識。本研究旨在評估母乳餵養對兒童泌尿道感染可能的保護作用。方法：本研究採用前瞻性病例─對照研究，選取50 名在出生後1 年內確診泌尿道感染的嬰兒，另50 名小於1 歲的健康嬰兒作為對照組。根據餵養方式再將這兩組嬰兒分為母乳餵養組、配方奶餵養組和混合餵養組各三組。結果：母乳餵養兒泌尿道感染發生的危險度較配方奶餵養兒和混合餵養兒明顯降低（OR=0.1，95%CI，0.027-0.329 和OR=0.33，95%CI，0.124-0.866）。混合餵養兒泌尿道感染發生的危險度又低於配方奶餵養兒（OR=0.3，95%CI，0.091-0.92）。母乳餵養時間越長，泌尿道感染發生的危險度越低（OR=0.29，95%CI，0.121-0.714）。結論：基於以上結果，母乳餵養對泌尿道感染有保護作用。