Table of Contents

HK J Paediatr (New Series)
Vol 13. No. 1, 2008

HK J Paediatr (New Series) 2008;13:46-52

Case Report

Hepatopulmonary Syndrome: An Unusual Presentation of Chronic Hypervitaminosis A
肝肺綜合征: 一例慢性維生素 A 過多症罕見的臨床表現

VWS Lau, DCY Lau, KF Huen


Vitamin supplementation is a frequent phenomenon in Hong Kong children for various reasons. Vitamin A is amongst the most frequently used vitamin presented in various 'fish oil' supplements, and its toxicity is being widely reported in literature. Hepatopulmonary syndrome is a triad of chronic liver disease; increased alveolar-arterial oxygen gradient; and evidence of intrapulmonary vascular dilatation (IPVD), and has been reported in a number of liver diseases but not in hypervitaminosis A before. We reported a case in which a family of three sisters suffered from hepatopulmonary syndrome as a result of hypervitaminosis A.

香港兒童因各種原因添加維生素是個常見的現象。在各種“魚油”添加中,維生素 A 是最常被用到的維生素,它的毒付作用在文獻中被廣泛報道。肝肺綜合徵是慢性肝臟疾病三聯徵;增加肺泡動脈血氧度;肺內血管擴張的證據(IPVD),該綜合徵在維生素 A 過多症中鮮有報導,雖然之前在一些肝臟疾病中已有報導。我們報導一患者,來自一個三姐妹家庭,因維生素 A 過多症而患肝肺綜合徵。

Keyword : Hepatopulmonary syndrome; Hypervitaminosis A; Vitamin A

關鍵詞:肝肺綜合徵、維生素 A 過多症、維生素 A


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