Table of Contents

HK J Paediatr (New Series)
Vol 12. No. 4, 2007

HK J Paediatr (New Series) 2007;12:293-296

Case Report

Bacillus Cereus Meningoencephalitis in a Neonate

S Puvabanditsin, A Zaafran, E Garrow, R Diwan, D Mehta, N Phattraprayoon


Neonatal meningoencephalitis caused by Bacillus cereus is rare. In most cases, the infection is fatal because of extensive damage and necrosis of infected tissue caused by the toxins produced by B. cereus. We report on a 17-day-old preterm neonate who developed B. cereus bacteraemia and severe haemorrhagic meningoencephalitis. The infant survived. The ultrasound, CT and MRI images showed pattern of haemorrhagic and early cavitating, selective white matter destruction. The interval from the time of recognition of illness to irreversible damage of the central nervous system was short which demonstrates a need for increase awareness, early diagnosis, and more-effective therapy. We describe the clinical course and a distinct neuroimaging characteristic for this organism.

新生兒蠟樣芽胞桿菌腦膜腦炎甚為罕見。多數致命感染的病例是因為蠟樣芽胞桿菌毒素造成感染組織廣泛損害及壞死。我們報導一例出生 17 天早產兒感染蠟樣芽胞桿菌及嚴重出血性腦膜腦炎。嬰兒存活了。超聲、 CT 及 MRI 影像學顯示出血的類型、早期空洞及選擇性白質損害。從確診該病至中樞神經系統不可逆損害之間的間隔時間是短暫的,故提高對疾病的認識、早期診斷及高效率的治療是需要的。

Keyword : Bacillus cereus; Meningoencephalitis; Neonate; White matter injury



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