KC Chow, GCF Chan, PL Khong, TWH Shek, SY Ha, YL Lau

Abstract

Ki-1-positive anaplastic large cell lymphoma is a common form of aggressive non-Hodgkin's lymphoma in children with a wide spectrum of clinical presentations. Uncommonly, it presents as a paraspinal tumour with spinal cord compression. Only a limited number of cases with similar presentation have so far been reported in the English literature. We reported a boy with paraspinal Ki-1-positive anaplastic large cell lymphoma initially presented with paraplegia. The patient achieved complete remission with chemotherapy plus local irradiation and regained full function with no residual neurological deficit.

Ki-1 間變性大細胞性淋巴瘤是兒童中常見的一種進展性淋巴瘤，具有廣泛的臨床症狀。但以脊髓旁腫瘤壓迫脊髓表現是罕見的。到目前為止，在英語文獻資料中僅有有限的類似病例報導。我們報導一例以雙下肢癱瘓為初發表現的脊髓旁 Ki-1 間變性大細胞性淋巴瘤的男孩病例。該病例經過化療和局部放療獲得完全緩解，肢體功能完全恢復，沒有留下神經系統的後遺症。