Table of Contents

HK J Paediatr (New Series)
Vol 9. No. 2, 2004

HK J Paediatr (New Series) 2004;9:109-113

Original Article

Sleep-disordered Breathing in Children with Duchenne Muscular Dystrophy

TK Wong, TNH Leung, BWY Young


Advances in Paediatric Polysomnography have led to increased recognition of sleep-disordered breathing in children suffering form Duchenne muscular dystrophy (DMD). Because of the unique physiological alterations during sleep, respiratory muscle dysfunction in DMD may be recognised during sleep early in the disease. Recognised patterns include: 1) hypoxaemia; 2) obstructive apnoea, central apnoea, and hypopnoea. These may have important contribution to development of progressive cardiorespiratory failure. Early diagnosis with nocturnal polysomnography is the most conclusive way to assess nocturnal respiratory insufficiency in DMD children. Potential use of non-invasive ventilatory support should be discussed with patient and care takers early in the disease.

Keyword : Duchenne muscular dystrophy; Sleep-disordered breathing; Polysomnography

Abstract in Chinese


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