 |
 |
HK J Paediatr (New Series)
Vol 12. No. 3,
2007
|
|
HK J Paediatr (New Series) 2007;12:194-198
Case Report
Medications for Improving Urine Output and Renal In sufficiency Following Surgery for Congenital Heart Disease: A Case Study
KLE Hon, JL Jefferies, SL Goldstein, JF Price, ED McKenzie, CD Fraser, S Stayer, AC Chang Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China KLE Hon ( 韓錦倫 ) MBBS, FAAP Divisions of Pediatric Cardiology, Pediatric Nephrology, Pediatric Cardiovascular Anesthesia, and Pediatric Cardiac Surgery, Texas Children Hospital, USA JL Jefferies MD, MPH SL Goldstein MD JF Price MD ED McKenzie MD CD Fraser MD S Stayer MD AC Chang MD, MBA Correspondence to: Prof KLE Hon Received February 28, 2006
Abstract We report the effects of various agents for treatment of renal insufficiency in the immediate post-operative period in a case of Fontan surgery. Because of the failing atriopulmonary Fontan, the patient underwent a total cavopulmonary connection, atrial septectomy, homograft patch angioplasty of the left pulmonary artery, modified MAZE procedure, and placement of a permanent pacemaker. Diuretics, dopamine and low-dose intravenous Fenoldopam were used for renal insufficiency intra- and postoperatively. The cardiovascular effects and renal function were documented during the use of these agents. Apart from transient hypotension, oliguria and impairment of renal function following cardiopulmonary bypass, there was no deleterious haemodynamic effect. Fenoldopam is a benzazepine derivative with selective dopamine-1 receptor agonist properties. At low doses, it has also been proposed that fenoldopam exerts effects on renal blood flow similar to that of dopamine. The availability of a new agent for postoperative use is attractive but further studies are warranted to explore its potential use in children following congenital heart surgery who are likely to have reduced renal function. Keyword : Congenital heart surgery; Fenoldopam; Renal insufficiency Abstract in Chinese
|
|
 |