Table of Contents

HK J Paediatr (New Series)
Vol 12. No. 3, 2007

HK J Paediatr (New Series) 2007;12:194-198

Case Report

Medications for Improving Urine Output and Renal In sufficiency Following Surgery for Congenital Heart Disease: A Case Study

KLE Hon, JL Jefferies, SL Goldstein, JF Price, ED McKenzie, CD Fraser, S Stayer, AC Chang


We report the effects of various agents for treatment of renal insufficiency in the immediate post-operative period in a case of Fontan surgery. Because of the failing atriopulmonary Fontan, the patient underwent a total cavopulmonary connection, atrial septectomy, homograft patch angioplasty of the left pulmonary artery, modified MAZE procedure, and placement of a permanent pacemaker. Diuretics, dopamine and low-dose intravenous Fenoldopam were used for renal insufficiency intra- and postoperatively. The cardiovascular effects and renal function were documented during the use of these agents. Apart from transient hypotension, oliguria and impairment of renal function following cardiopulmonary bypass, there was no deleterious haemodynamic effect. Fenoldopam is a benzazepine derivative with selective dopamine-1 receptor agonist properties. At low doses, it has also been proposed that fenoldopam exerts effects on renal blood flow similar to that of dopamine. The availability of a new agent for postoperative use is attractive but further studies are warranted to explore its potential use in children following congenital heart surgery who are likely to have reduced renal function.

Keyword : Congenital heart surgery; Fenoldopam; Renal insufficiency

Abstract in Chinese


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