Table of Contents

HK J Paediatr (New Series)
Vol 1. No. 1, 1996

HK J Paediatr (New Series) 1996;1:48-52

Original Article

Bone Marrow Transplant for Non-Malignant Diseases

CK Li, MP Yuen, MK Shing, KW Chik, DH Lai, SH Cheng, KS Tsang


Twenty patients received bone marrow transplant for treatment of non-malignant diseases over a four-year period. Sixteen patients were suffering from transfusion dependent thalassaemia, three patients from severe aplastic anaemia and one from chronic granulomatous disease. The donors were all HLA identical siblings of the patients. All the patients engrafted successfully after bone marrow transplant and there was no early mortality within the first three months after transplant. One thalassaemia patient rejected the bone marrow at five months after transplant and subsequently died from infection. The other nineteen patients were now all free from the primary diseases at a median follow up of 27 months (range 2 to 49 months). There were no long term complications in the survivors. In conclusion, bone marrow transplant provided a high chance of cure for non-malignant diseases.

Keyword : Bone marrow transplant; Chronic granulomatous disease; Severe aplastic anaemia; Thalassaemia

Abstract in Chinese


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