KS Lun, LKH Poon, WH Lee

Abstract

We report here the use of continuous infusion of prostacyclin into the pulmonary artery in a newborn with severe pulmonary hypertension of newborn complicating meconium aspiration. Use of intravenous vasodilators failed to reverse the hypoxaemia while causing severe systemic hypotension. The use of prostacyclin infusion in the pulmonary artery decreased the pulmonary arterial pressure and significantly improved systemic oxygenation. There was no deterioration of blood pressure. The infant was successfully managed with good outcome.