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HK J Paediatr (New Series)
Vol 5. No. 1,
2000
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HK J Paediatr (New Series) 2000;5:48-51
Case Report
Three Children with Failure to Thrive and Recurrent Infections
TF Leung, CK Li, MMK Shing, KW Chik, PMP Yuen Department of Paediatrics, 6/F, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T., Hong Kong, China TF Leung ( 梁廷勳 ) MBChB(CUHK), MRCP(UK), FHKAM(Paed) CK Li ( 李志光 ) MBBS(HKU), FRCP(Edin), FRCPCH MMK Shing ( 成明光 ) MBBS(HKU), FRCP(Edin & Glas) KW Chik ( 戚其威 ) MBChB(CUHK), MRCP(UK), FHKAM(Paed) PMP Yuen ( 阮文賓 ) MD(Sask), FRCPC, DABPaed Correspondence to: Dr TF Leung Received August 7, 1999
Abstract We report three young children with common variable immunodeficiency that presented with failure to thrive as well as recurrent viral, bacterial or fungal infections. They had abnormal humoral and cellular immune functions as well as altered functions of granulocytes and natural killer cells. Our oldest boy died from severe pneumonia whereas the other two patients are free from serious infection on followup. Although common variable immunodeficiency typically affects young adults, this diagnosis should also be considered in infants and young children who suffered from atypical or recurrent infections. Thorough immunological investigations should be performed in these patients. Keyword : Scrub typhus; Orientia tsutsugamushi Abstract in Chinese
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