ASW Ku, KW Lee, KL Wan, WKY Chan

Abstract

Opportunistic infection with multiple organisms is known to occur in immunocompromised patients. In this article, we report a 14 years old girl, with 4 years history of systemic lupus erythematosus, who developed pneumonia caused by Pneumocystis carinii and cytomegalovirus. She responded to combination therapy of intravenous sulfamethoxazole-trimethoprim and ganciclovir. She shared some common risk factors in SLE for developing Pneumocystis carinii pneumonia, including active disease with renal involvement, history of receiving immunosuppressant, and lymphopenia. The author recommends the early use of bronchoalveolar lavage to investigate pneumonia in immunocompromised patients.