Table of Contents

HK J Paediatr (New Series)
Vol 29. No. 4, 2024

HK J Paediatr (New Series) 2024;29:230-241

Original Article

Research on Establishing a Core Outcome Set for Clinical Research of Traditional Chinese Medicine in Children with Abdominal Henoch-Schonlein Purpura

J Tong, C Liang, H Dong, X Peng, Y Hu, J Liu, Y Zhang, Y Yang, Y Liu


Abstract

Objective: This study aims to investigate and analyse the outcomes reported in c and to establish the core outcome set (COS) for children with abdominal Henoch-Schonlein purpura (HSP). Methods: Following standard operating procedures for COS development, an systematic review was conducted to extract outcomes from the relevant clinical studies, then conducted two rounds of Delphi study, after that a consensus meeting was held to finalise COS. Results: A total of 6 outcomes were included in the final COS: the degree of abdominal pain, time to abdominal pain disappearance, and time to bloody stool disappearance, and the incidence of adverse reactions or complications. Conclusion: A COS comprising 6 outcomes for abdominal HSP has been established, providing a valuable reference for the selection of outcomes in future clinical trials in this area.

Keyword : Children; Core outcome set; IgA vasculitis; Purpura


 
 

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