DCY Au, NC Fong, SC Ling

Abstract

Acute leukaemia is the most common malignancy in childhood, and could be associated with life-threatening complications at presentation such as tumour-lysis syndrome. Hyperleukocytosis with leukostasis is less commonly recognised. Clinical presentation could be confusingly overlapping with tumour-lysis. High vigilance and early initiation of medical cytoreduction therapy remain as the key to minimising early mortality and morbidity.