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HK J Paediatr (New Series)
Vol 27. No. 2,
2022
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HK J Paediatr (New Series) 2022;27:100-106
Original Article
Predictors of Remission in Childhood Immune Thrombocytopenia
FLY Chan, GPG Fung, LTW Chan, WK Chiu Department of Paediatrics and Adolescent Medicine, Tseung Kwan O Hospital, 2 Po Ning Lane, Hang Hau, Tseung Kwan O, N.T., Hong Kong SAR, China FLY Chan(陳令貽) FHKCPaed, FHKAM(Paed) LTW Chan(陳子宏) FHKCPaed, FHKAM(Paed) Department of Paediatrics and Adolescent Medicine, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Kowloon, Hong Kong SAR, China GPG Fung(馮寶姿) FHKCPaed, FHKAM(Paed) WK Chiu(趙華強) FHKCPaed, FHKAM(Paed) Correspondence to: Dr FLY Chan Email: cly065@ha.org.hk Received February 22, 2020
Abstract Background: Demographic and clinical features of childhood immune thrombocytopenia (ITP) in Hong Kong were described and the clinical predictors of ITP remission were identified. Methods: We conducted a 15-year retrospective analysis of all children with newly diagnosed ITP in two regional hospitals in Hong Kong. Demographic and clinical features of childhood ITP were described. Clinical predictors of remission by 12 months were analysed by a logistic regression model. Results: One hundred and eleven cases of newly diagnosed ITP were analysed, among which 85 (77%) recovered by 12 months while 26 (23%) of them developed a chronic course. Remission was associated with the following predictors: platelet count ≤10x109/L (p=0.034), age ≤24 months (p=0.013) and acute onset of symptoms (p=0.001). Conclusions: We presented the demographic and clinical features of childhood ITP in the local population. Clinical predictors of remission were identified as a guide for disease monitoring. Keyword : Children; Chronic; ITP; Newly diagnosed; Thrombocytopenia
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