Table of Contents

HK J Paediatr (New Series)
Vol 26. No. 3, 2021

HK J Paediatr (New Series) 2021;26:158-160

Case Report

An Extremely Rare Association of Cleft Lip and Palate, Basal Sphenoethmoidal Cephalocele and Corpus Callosal Agenesis in a Three-month Old Patient Presenting with Facial Cleft and Nasal Mass

RJDL Urgel, GG Viterbo


We present an infant who was born with a midline facial cleft and clinically apparent nasal mass. Non-enhanced facial computed tomography (CT) revealed the cleft lip and palate, and nasal mass - the latter was better defined as a sac containing meninges, cerebrospinal fluid and what appears to be dysplastic brain parenchyma. Further evaluation of the CT images revealed agenesis of the corpus callosum and colpocephaly. A non-enhanced magnetic resonance imaging was unable to be performed as patient was lost to follow-up. The need for neuroimaging may not always be implied in cases of cleft lip and palate. However, the presence of other findings such as a nasal mass may warrant investigation with cross-sectional imaging to determine its aetiology, define the extent of the midline facial cleft and look for other possible anomalies.

Keyword : Agenesis of corpus callosum; Encephalocele; Neuroimaging; Orofacial cleft


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