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HK J Paediatr (New Series)
Vol 26. No. 1,
2021
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HK J Paediatr (New Series) 2021;26:38-41
Case Report
Restless Leg Syndrome in a Child and an Adolescent with Excellent Responses to Iron Replacement Therapy
CPL Hoo, WL Lau, CH Ko Department of Paediatrics and Adolescent Medicine, Caritas Medical Centre, 111 Wing Hong Street, Sham Shui Po, Kowloon, Hong Kong SAR, China CPL Hoo(胡沛麟) MRCPCH, MBChB (CUHK) WL Lau(劉慧齡) MRCPCH, DCH (International RCPCH), FHKAM (Paediatrics) CH Ko(高震雄) FHKAM (Paediatrics), FRCP (Glasg) Correspondence to: Dr CPL Hoo Email: calvinhoo2002@gmail.com Received May 27, 2019
Abstract We report symptomatic Restless Leg Syndrome (RLS) in an adolescent with normal intelligence, and a young autistic child who suffered from stroke. Both were found to have low serum ferritin levels. In both cases, iron replacement therapy resulted in complete remission of symptoms. The findings substantiate the hypothesis that brain iron deficiency is implicated in the pathophysiology of RLS. Ferritin level below 112 pmol/L (50 ng/ml) serves as a useful threshold to aid diagnosis and treatment in symptomatic young children who cannot tell their discomfort. Keyword : Iron deficiency; Iron supplementation; Restless leg syndrome; Serum ferritin
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