Table of Contents

HK J Paediatr (New Series)
Vol 26. No. 1, 2021

HK J Paediatr (New Series) 2021;26:38-41

Case Report

Restless Leg Syndrome in a Child and an Adolescent with Excellent Responses to Iron Replacement Therapy

CPL Hoo, WL Lau, CH Ko


We report symptomatic Restless Leg Syndrome (RLS) in an adolescent with normal intelligence, and a young autistic child who suffered from stroke. Both were found to have low serum ferritin levels. In both cases, iron replacement therapy resulted in complete remission of symptoms. The findings substantiate the hypothesis that brain iron deficiency is implicated in the pathophysiology of RLS. Ferritin level below 112 pmol/L (50 ng/ml) serves as a useful threshold to aid diagnosis and treatment in symptomatic young children who cannot tell their discomfort.

Keyword : Iron deficiency; Iron supplementation; Restless leg syndrome; Serum ferritin


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