TWY Cheung, CH Li, TL Ku, SY Lam, SN Wong

Abstract

Sjögren's syndrome is a chronic inflammatory autoimmune disorder characterised by lymphocytic infiltration and destruction of the salivary and lacrimal glands by auto-antibodies. Although considered a benign disease, it is associated with a range of complications manifested in multiple organ systems and even higher risk for developing lymphoma, one of which is mucosa-associated lymphoid tissue (MALT) lymphoma. It is a rare complication and predominantly occurs in adults, with limited reports in the paediatric population. We report a case of MALT lymphoma presenting with a left parotid mass and subglottic stenosis in a 13-year-old girl with known history of Sjögren's syndrome. Although cases of children with Sjögren's syndrome have been reported, the development of MALT lymphoma in children presenting with subglottic stenosis is rarely reported. Clinicians should be alerted for the possibility of malignant infiltration.