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Case Report A Rare Tumour in Chinese: The First Reported Case of Paediatric Uveal Melanoma in Hong Kong and Literature Review 華人罕見腫瘤一例：香港兒童葡萄膜黑色素瘤的首例報告附文獻綜述 CH Fu, JJT Chan, HL Yuen, CW Luk Abstract Differential diagnosis of paediatric malignant ocular tumour is limited, with retinoblastoma being the most common among all ethnicities in the world. The incidence of paediatric malignant cutaneous melanoma among Asians is low and paediatric ocular melanoma is even scarce. We reported the first case of paediatric malignant ocular melanoma in Hong Kong, a 10-year-old boy with a large localised choroidal melanoma managed by enucleation uneventfully. Genetic tests for high-risk features were negative. He remained under close surveillance with no evidence of metastasis 1 year post enucleation. 兒童眼部惡性腫瘤的鑒別診斷經驗有限，世界上所有種族均以視網膜母細胞瘤最為常見。亞洲人中兒童惡性皮膚黑色素瘤的發病率低下，兒童眼部黑色素瘤就更是罕見。作者報告香港首例兒童眼部惡性黑色素瘤，為10歲男孩，患巨大局部脈絡膜黑色素瘤，通過手術順利摘除。高危特徵的基因測試均為陰性。術後1 年，病童目前仍然進行密切觀察，無腫瘤轉移情況出現。 Keyword : BAP1 mutation; Choroidal; Metastasis; Monosomy 3; Uveal melanoma 關鍵詞：BAP1突變、脈絡膜、腫瘤轉移、3號染色體單體、葡萄膜黑色素瘤
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