Table of Contents

HK J Paediatr (New Series)
Vol 24. No. 4, 2019

HK J Paediatr (New Series) 2019;24:179-183

Original Article

Treatment Outcome for Therapy-related Myeloid Neoplasm in Children

FWT Cheng, GKS Lam, TTW Chow, MMK Shing, V Lee, CK Li


We report the clinical course and treatment outcome of 7 patients with therapy-related myeloid neoplasm in the past 32 years. The primary conditions included both solid tumours and leukaemia. The time interval between onset of primary disease and therapy-related neoplasm ranged from 1.2 years to 4.4 years. In contrary to the reported high treatment-related mortality and morbidity, with fludarabine-based salvage chemotherapy, stringent supportive care and early allogeneic stem cell transplantation as consolidative therapy, long term survival can be achieved in 5 out of 7 patients. Long-term follow-up is warranted for survivors with oncology patients who received chemotherapy.

Keyword : Myeloid Neoplasm; Therapy-related

Abstract in Chinese


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