Table of Contents

HK J Paediatr (New Series)
Vol 23. No. 2, 2018

HK J Paediatr (New Series) 2018;23:185-187

Case Report

Reye's Syndrome Arising from the Treatment of Kawasaki Disease

EJ Su, JH Hsieh, CC Hsu, KT Chen


We report on a 20-month-old girl who presented with vomiting and lethargy after being discharged from the ward following treatment for Kawasaki disease. The symptoms occurred after five days of aspirin therapy. The clinical features and laboratory tests proved the presence of Reye's syndrome and she recovered after intensive treatment. In addition, we collected three similar reported cases. All the patients came from East Asia and the mortality rate reached 50%. Since salicylate is an effective and imperative treatment for Kawasaki disease, paediatricians and emergency physicians can consider using a low dose of aspirin (3-5 mg/kg) as maintenance therapy, discontinuing aspirin for a short period or replace it with dipyridamole during influenza or varicella epidemics, and having a high index of suspicion of Reye's syndrome in patients with Kawasaki disease.

Keyword : Aspirin; Complication; Kawasaki disease; Reye's syndrome; Salicylate

Abstract in Chinese


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