PT Tsai, YW Chen

Abstract

Garré's sclerosing osteomyelitis is a chronic osteomyelitis with proliferative periostitis (periosteitis ossificans) that mainly affects children and adolescents. The aetiology of this disease of jaw bone is associated with mild irritation or dental infection. However, Garré's sclerosing osteomyelitis of mandible originating from trauma and resolving under medication treatment is rarely reported. A case of Garré's osteomyelitis of mandible associated with trauma history is presented. Under appropriate diagnosis and treatment strategy, this inflammatory disease of mandible gradually subsided despite of the resemblance of distinguished malignancies, such as osteosarcoma and chondrocarcoma. We reported this case as a reminder for clinicians that some benign diseases may masquerade as malignancies, and careful systematic review and approach to patients will lead to correct diagnosis and suitable treatment.

Garré's硬化性骨髓炎是一種發生於兒童和青少年的慢性骨髓炎伴增殖性骨膜炎（骨化骨膜炎）。該病在下頜的發生與輕度刺激或口腔感染相關。然而由外傷所致並能夠通過藥物治療得以控制的下頜骨Garr?s硬化性骨髓炎病例則少有報告。本文記述了一外傷史相關的下頜骨Garré's骨髓炎病例，其中通過正確的診斷和治療，雖然仍然表現出類似惡性病變如骨肉瘤或軟骨肉瘤的情況，該炎症性疾病得到了控制並逐漸消退。我們報告該病例的目的在於提醒臨床醫生某些良性疾病可能表現出類似惡性疾病的徵象，只有細緻而系統的病例回顧及方法選擇才能讓我們做出正確的診斷和治療。