ZX Li, JD Gao, HM Yu, KW Jiang

Abstract

An 11-year and 7-month-old Chinese boy with Guillain-Barré syndrome (GBS) manifested headaches and seizures after the administration of intravenous immunoglobulin (IVIg). Magnetic resonance imaging revealed posterior reversible encephalopathy syndrome (PRES). Several previous reports described PRES associated with IVIg, but few in children. We suggest that this syndrome should be considered in children with GBS and/or administration of IVIg as a neurologic complication. This report reviews the literature on this unusual association and discusses possible pathophysiological mechanisms.

一名中國籍男孩11歲7個月大，患有格林－巴厘綜合徵，在靜脈輸注免疫球蛋白（IVIg）後出現頭痛與抽搐，磁力共振影像顯示後部可逆性腦病綜合徵（PRES）。過往有一些病例報導用IVIg後出現PRES，但兒童很少出現此現象。我們認為這種綜合徵可能是格林－巴厘綜合症患兒用或不用IVIg的神經學併發症。本文回顧了這種罕見關聯的文獻，探討了可能出現的病理生理機制。