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HK J Paediatr (New Series)
Vol 21. No. 3,
2016
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HK J Paediatr (New Series) 2016;21:197-200
Case Report
Two Cases of Kawasaki Disease Shock Syndrome
SWY To, CLS Yan, NC Fong, CW Leung Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital, 2-10 Princess Margaret Hospital Road, Kwai Chung, N.T., Hong Kong, China SWY To (杜詠恩) MBBS, MRCPCH CLS Yan (甄麗嬋) MBBS, MRCPCH NC Fong (方乃聰) FHKCPaed, FHKAM (Paed) CW Leung (梁志偉) FRCP, FRCPCH Correspondence to: Dr SWY To Received July 9, 2015
Abstract Kawasaki disease shock syndrome (KDSS) is a newer entity being better recognised recently, which is defined as Kawasaki disease features plus systolic hypotension or clinical signs of poor perfusion. Patients with KDSS typically have more heightened levels of inflammatory markers and greater risks of coronary artery abnormalities, mitral regurgitation and persistent myocardial dysfunction. They also have greater likelihood of intravenous immunoglobulin (IVIG) resistance requiring additional anti-inflammatory treatment. We report two cases of KDSS presenting with shock, both with IVIG resistance and coronary arteries involvement. Clinicians should maintain high index of suspicion for KDSS to avoid delay in diagnosis and to facilitate timely treatment by IVIG. Keyword : Complications; Immunoglobulins; Kawasaki disease; Paediatric intensive care units; Shock Abstract in Chinese
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