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HK J Paediatr (New Series)
Vol 21. No. 2,
2016
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HK J Paediatr (New Series) 2016;21:102-104
Case Report
Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Induced by Cefazolin and Gentamicin in a Child
K Yilmaz, Z Gunduz, F Tahan, HH Akar Department of Pediatric Nephrology, Erciyes University, Kayseri, Turkey K Yilmaz MD Z Gunduz MD(Prof) Department of Pediatric Allergy, Erciyes University, Kayseri, Turkey F Tahan MD(Prof) HH Akar MD Correspondence to: Dr K Yilmaz Received June 4, 2015
Abstract Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, is an uncommon, acute and severe life-threatening systemic disease. DRESS syndrome is characterised by fever, skin rash, lymph node enlargement, and internal organ involvement. The most common culprit drugs are anticonvulsants and allopurinol. We first reported a case of DRESS syndrome induced by cefazolin and gentamicin in a child. We aimed to emphasize the severity of renal damage and the dramatic response to short term intravenous and oral steroid therapy. Keyword : DRESS syndrome; Drug hypersensitivity; Eosinophilia; Interstitial nephritis Abstract in Chinese
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