Table of Contents

HK J Paediatr (New Series)
Vol 25. No. 3, 2020

HK J Paediatr (New Series) 2020;25:159-165

Original Article

Pain Response Comparison Between Two Different Vaccinations
兩種疫苗的疼痛反應對比

B Çuhaci Çakir, TR Şayli, A Kara Uzun, U Suiçmez


Abstract

We aimed to determine the effect of the order of 2 different intramuscular vaccine injection 13-valent pneumococcal conjugate (PCV-13) vaccine and diphtheria and tetanus toxoids, acellular pertussis, inactivated poliovirus and Haemophilus influenzae type b (Hib) (DTaP-IPV-Hib) conjugate vaccine by using Modified Behaviour Pain Scale (MBPS) at the same visit. The 72 infants at the 4th and 54 infants at the 6 months of age were injected either PCV-13 first or DTaP-IPV-Hib first followed by the other vaccine/vaccines. After first vaccine, she was recorded the crying time and pain score according to the MBPS. Mean cry duration time after injection was significantly shorter when DTaP-IPV-Hib vaccine was administered first compared with PCV-13 vaccine (p<0.001). If DTaP-IPV-Hib vaccine was done first, total MBPS score was significantly lower than if PCV-13 vaccine was done first (p<0.001). When multipl vaccines are injected at the same visit, they should be administred in order of increasing painfulness.

作者針對順序接種的2種肌肉注射疫苗:13價肺炎球菌疫苗(PCV-13)和百白破-滅活天花-流感嗜血桿菌 B聯合疫苗(DTaP-IPV-Hib),在相同疫苗注射時,用改良行為疼痛量表(MBPS)進行效果測定。72例4 月齡嬰兒和54例6月齡嬰兒分別先注射PCV-13或DTaP-IPV-Hib疫苗,下次再接種另一種疫苗。首次疫苗接種後,根據MBPS量表記錄哭鬧時間和疼痛評分。首次注射DTaP-IPV-Hib疫苗時,對比PCV-13疫苗,注射後的平均哭鬧持續時間顯著縮短(p<0.001)。如果首次注射為DTaP-IPV-Hib疫苗,對比PCV-13疫苗,總MBPS評分顯著降低(p<0.001)。當同一次進行多種疫苗接種時,接種應該是疼痛增加的順序。

Keyword : 13-valent pneumococcal conjugate vaccine; Diphtheria and tetanus toxoids, acellular pertussis, inactivated poliovirus and Haemophilus influenzae type b (Hib) conjugate vaccine; Pain; Vaccination

關鍵詞:13價肺炎球菌聯合疫苗、百日咳-白喉-破傷風-滅活天花-流感嗜血桿菌B型聯合疫苗、疼痛、疫苗接種

 
 

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