Table of Contents

HK J Paediatr (New Series)
Vol 24. No. 4, 2019

HK J Paediatr (New Series) 2019;24:245-248

Case Report

A Rare Case of Mucosa-associated Lymphoid Tissue (MALT) Lymphoma in a Child with Sjögren's Syndrome Presenting with Parotid Mass and Subglottic Stenosis
罕見粘膜相關淋巴組織(MALT)淋巴瘤帶腮腺包塊和聲門下狹窄乾燥綜合徵一例

TWY Cheung, CH Li, TL Ku, SY Lam, SN Wong


Abstract

Sjögren's syndrome is a chronic inflammatory autoimmune disorder characterised by lymphocytic infiltration and destruction of the salivary and lacrimal glands by auto-antibodies. Although considered a benign disease, it is associated with a range of complications manifested in multiple organ systems and even higher risk for developing lymphoma, one of which is mucosa-associated lymphoid tissue (MALT) lymphoma. It is a rare complication and predominantly occurs in adults, with limited reports in the paediatric population. We report a case of MALT lymphoma presenting with a left parotid mass and subglottic stenosis in a 13-year-old girl with known history of Sjögren's syndrome. Although cases of children with Sjögren's syndrome have been reported, the development of MALT lymphoma in children presenting with subglottic stenosis is rarely reported. Clinicians should be alerted for the possibility of malignant infiltration.

乾燥綜合徵為一種慢性炎症性自身免疫疾病,以唾液腺和淚腺受到淋巴細胞浸潤和自身抗體破壞為特徵。雖然被視作非癌症疾病,但該病與一系列多器官系統併發症相關,其中甚至包括可惡化為淋巴瘤的高風險,其中一種是粘膜相關淋巴組織(MALT)淋巴瘤。它是一種罕見併發症,主要見於成人,甚少兒童病例報告。作者報告MALT淋巴瘤一例,病人為一名左側腮腺包塊和聲門狹窄。13歲女孩,有乾燥綜合徵病史。雖然乾燥綜合徵兒童病例已見有報告,但是惡化為MALT淋巴瘤伴聲門狹窄則甚為罕見。醫生應該警惕這些病人出現惡性腫瘤的可能性。

Keyword : Children; MALT; Mucosa-associated lymphoid tissue lymphoma; Sjögren's syndrome; Subglottic

關鍵詞:兒童、罕見粘膜相關淋巴組織、粘膜相關淋巴組織淋巴瘤、乾燥綜合徵( Sjögren's Syndrome)、聲門狹窄

 
 

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